C57BL/6NCrl-Cd38em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12846
Citation informationRRID:IMSR_EM:12846 

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International strain nameC57BL/6NCrl-Cd38em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolCd38em1(IMPC)Ccpcz
Gene/Transgene symbolCd38

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal digit morphology / IMPC
  • decreased NK T cell number / IMPC
  • increased NK cell number / IMPC
  • decreased CD4-positive, alpha-beta T cell number / IMPC
  • decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • decreased CD4-positive NK T cell number / IMPC
  • decreased memory-marker CD4-positive NK T cell number / IMPC
  • decreased T-helper cell number / IMPC
  • decreased effector memory T-helper cell number / IMPC
IMPC phenotypes (gene matching)
  • abnormal digit morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • decreased CD4-positive NK T cell number / IMPC
  • decreased NK T cell number / IMPC
  • decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
  • abnormal thymus morphology / IMPC
  • decreased memory-marker CD4-positive NK T cell number / IMPC
  • decreased effector memory T-helper cell number / IMPC
  • enlarged thymus / IMPC
  • decreased CD4-positive, alpha-beta T cell number / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • increased NK cell number / IMPC
  • decreased T-helper cell number / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

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    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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