C57BL/6NCrl-Prss48^{em1(IMPC)Ccpcz}/Ph

Status	Under development - register interest
EMMA ID	EM:12780
Citation information	RRID:IMSR_EM:12780 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6NCrl-Prss48^{em1(IMPC)Ccpcz}/Ph
Alternative name
Strain type	Endonuclease-mediated
Allele/Transgene symbol	Prss48^{em1(IMPC)Ccpcz}
Gene/Transgene symbol	Prss48

Information from provider

Provider	Institute of Molecular Genetics
Provider affiliation	Department of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic information	This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic information	Potential phenotyping data in the IMPC portal
References	None available

Information from EMMA

Archiving centre	Institute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)

abnormal spleen morphology / IMPC
abnormal thymus morphology / IMPC
enlarged thymus / IMPC
small seminal vesicle / IMPC
abnormal seminal vesicle morphology / IMPC
abnormal eye morphology / IMPC
abnormal digit morphology / IMPC
abnormal kidney morphology / IMPC
abnormal caudal vertebrae morphology / IMPC
decreased lean body mass / IMPC
abnormal vertebral arch morphology / IMPC
decreased respiratory quotient / IMPC

IMPC phenotypes (gene matching)

small seminal vesicle / IMPC
abnormal digit morphology / IMPC
abnormal caudal vertebrae morphology / IMPC
abnormal spleen morphology / IMPC
decreased respiratory quotient / IMPC
abnormal thymus morphology / IMPC
abnormal seminal vesicle morphology / IMPC
abnormal eye morphology / IMPC
enlarged thymus / IMPC
abnormal kidney morphology / IMPC
abnormal vertebral arch morphology / IMPC
decreased lean body mass / IMPC

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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C57BL/6NCrl-Prss48em1(IMPC)Ccpcz/Ph