- kyphosis / IMPC
- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal spleen morphology / IMPC
- abnormal thymus morphology / IMPC
- enlarged thymus / IMPC
- abnormal ovary morphology / IMPC
- abnormal testis morphology / IMPC
- small testis / IMPC
- abnormal skin morphology / IMPC
- abnormal spine curvature / IMPC
- decreased circulating potassium level / IMPC
- preweaning lethality, incomplete penetrance / IMPC
C57BL/6NCrl-Ak7em1(IMPC)Ccpcz/Ph
Status | Under development - register interest |
EMMA ID | EM:12777 |
Citation information | RRID:IMSR_EM:12777 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NCrl-Ak7em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Ak7em1(IMPC)Ccpcz |
Gene/Transgene symbol | Ak7 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Non-syndromic male infertility due to sperm motility disorder / Orphanet_276234
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal spine curvature / IMPC
- enlarged thymus / IMPC
- abnormal spleen morphology / IMPC
- abnormal thymus morphology / IMPC
- kyphosis / IMPC
- abnormal testis morphology / IMPC
- abnormal ovary morphology / IMPC
- enlarged heart / IMPC
- preweaning lethality, incomplete penetrance / IMPC
- abnormal skin morphology / IMPC
- small testis / IMPC
- abnormal heart morphology / IMPC
- decreased circulating potassium level / IMPC
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