C57BL/6NCrl-Bmp6em1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:12731
International strain nameC57BL/6NCrl-Bmp6em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolBmp6em1(IMPC)Ccpcz
Gene/Transgene symbolBmp6

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • kyphosis / IMPC
  • abnormal salivary gland morphology / IMPC
  • decreased body weight / IMPC
  • decreased locomotor activity / IMPC
  • decreased startle reflex / IMPC
  • abnormal pancreas morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal brain morphology / IMPC
  • increased mean corpuscular volume / IMPC
  • increased circulating alanine transaminase level / IMPC
  • abnormal spine curvature / IMPC
  • increased brain size / IMPC
  • decreased heart rate / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased hemoglobin content / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating iron level / IMPC
IMPC phenotypes (gene matching)
  • abnormal salivary gland morphology / IMPC
  • increased circulating iron level / IMPC
  • abnormal pancreas morphology / IMPC
  • increased brain size / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • increased hemoglobin content / IMPC
  • decreased body weight / IMPC
  • decreased startle reflex / IMPC
  • kyphosis / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased heart rate / IMPC
  • increased mean corpuscular volume / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • abnormal spine curvature / IMPC
  • decreased locomotor activity / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • abnormal brain morphology / IMPC
  • abnormal skin morphology / IMPC
MGI phenotypes (gene matching)
  • decreased body length / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • abnormal sternum ossification / MGI
  • abnormal sternum manubrium morphology / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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