MP1.BP1-Im3Bioz:BP1/DnmOrl
| Status | Available to order |
| EMMA ID | EM:00127 |
| International strain name | MP1.BP1-Im3Bioz:BP1/DnmOrl |
| Alternative name | LcH8-30 |
| Strain type | Other |
| Allele/Transgene symbol | Im3Bioz:BP1 |
| Gene/Transgene symbol | Im3 |
Information from provider
| Provider | D Mouton |
| Provider affiliation | Institut Curie |
| Phenotypic information | Several distinct chromosomal segments were identified by cosegregation analysis of polymorphic markers with antibody responsiveness in an F2 cross between high (H) and low (L) antibody responder lines of Biozzi mice. The effect associated with the relevant markers has been investigated in backcross populations (toward the L line) bred from H and L mice made coisogenic at the H-2 locus. Mice were individually tested for immune phenotype: antibody titres against SRBC (sheep red blood cells), at different times after optimal immunization. Four successive backcrosses to L line were analysed for 17 microsatellite markers and for antibody responsiveness. The LcH (low congenic to high) 8-30 strain has the chromosomal region flanked by two microsatellites D8Mit9 and D8Mit31 (at 32 cM from centromere). |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- Identification of two quantitative trait loci involved in antibody production on mouse chromosome 8.;Puel A, Mevel J C, Bouthillier Y, Decreusefond C, Fridman W H, Feingold N, Mouton D, ;1998;Immunogenetics;47;326-31; 9472069