C57BL/6NCrl-Apbb1ipem1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12692
Citation informationRRID:IMSR_EM:12692 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Apbb1ipem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolApbb1ipem1(IMPC)Ccpcz
Gene/Transgene symbolApbb1ip

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • increased leukocyte cell number / IMPC
  • increased neutrophil cell number / IMPC
  • increased monocyte cell number / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal testis morphology / IMPC
  • enlarged testis / IMPC
  • increased mean platelet volume / IMPC
  • increased kidney weight / IMPC
  • increased spleen weight / IMPC
  • increased eosinophil cell number / IMPC
  • decreased blood urea nitrogen level / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased red blood cell distribution width / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • increased airway resistance / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
IMPC phenotypes (gene matching)
  • abnormal spleen morphology / IMPC
  • increased mean platelet volume / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • increased leukocyte cell number / IMPC
  • abnormal thymus morphology / IMPC
  • increased effector memory CD8-positive, alpha-beta T cell number / IMPC
  • enlarged testis / IMPC
  • increased neutrophil cell number / IMPC
  • enlarged thymus / IMPC
  • increased red blood cell distribution width / IMPC
  • increased kidney weight / IMPC
  • decreased CD8-positive, naive alpha-beta T cell number / IMPC
  • abnormal testis morphology / IMPC
  • decreased blood urea nitrogen level / IMPC
  • increased monocyte cell number / IMPC
  • increased spleen weight / IMPC
  • enlarged spleen / IMPC
  • increased eosinophil cell number / IMPC
  • increased airway resistance / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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