MP1.BP1-Im4Bioz:BP1/DnmOrl
| Status | Available to order |
| EMMA ID | EM:00126 |
| Citation information | RRID:IMSR_EM:00126 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | MP1.BP1-Im4Bioz:BP1/DnmOrl |
| Alternative name | LcH6 |
| Strain type | Other |
| Allele/Transgene symbol | Im4Bioz:BP1 |
| Gene/Transgene symbol | Im4 |
Information from provider
| Provider | D Mouton |
| Provider affiliation | Institut Curie |
| Phenotypic information | The H (high antibody-responder) progenitors of F1 hybrids were derived from the H subline made coisogenic for the L (low antibody-responder) line H-2 haplotype by 12 consecutive backcrosses. Four consecutive backcrosses towards the L line and one intercross yielded LcH6 population. Mice were individually tested for immune phenotype: antibody titres against SRBC (sheep red blood cells), at different times after optimal (5.108 SRBC/mouse) immunization. The LcH (low congenic to high) 6 strain has the chromosomal region flanked by two microsatellites D6Mit5 and D6Mit10 (at 36 and 50 cM from centromere, respectively) that are linked with Ab (quantitative antibody) responsiveness. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Literature references
- Toward genetic dissection of high and low antibody responsiveness in Biozzi mice.;Puel A, Mevel J C, Bouthillier Y, Feingold N, Fridman W H, Mouton D, ;1996;Proceedings of the National Academy of Sciences of the United States of America;93;14742-6; 8962125