C57BL/6NCrl-Rnf208em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12586
Citation informationRRID:IMSR_EM:12586 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Rnf208em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolRnf208em1(IMPC)Ccpcz
Gene/Transgene symbolRnf208

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • decreased body weight / IMPC
  • abnormal lymph node morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • abnormal QT variability / IMPC
  • increased eosinophil cell number / IMPC
  • abnormal gallbladder morphology / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • enlarged gallbladder / IMPC
  • increased grip strength / IMPC
  • increased circulating creatine kinase level / IMPC
  • increased lung tissue damping / IMPC
IMPC phenotypes (gene matching)
  • abnormal QT variability / IMPC
  • enlarged gallbladder / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal gallbladder morphology / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased circulating alanine transaminase level / IMPC
  • enlarged lymph nodes / IMPC
  • increased eosinophil cell number / IMPC
  • abnormal lymph node morphology / IMPC
  • enlarged thymus / IMPC
  • decreased body weight / IMPC
  • enlarged heart / IMPC
  • abnormal heart morphology / IMPC
  • increased grip strength / IMPC
  • increased circulating creatine kinase level / IMPC
  • increased lung tissue damping / IMPC

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Register interest

Availabilities

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    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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