ADD16282

Status	Available to order
EMMA ID	EM:12558
International strain name	ADD16282
Alternative name	ADD16282
Strain type	Induced Mutant Strains : Chemically-induced
Allele/Transgene symbol	ADD16282
Gene/Transgene symbol	ADD16282

Information from provider

Provider	Paul B. Selby
Provider affiliation	Biology Division, Oak Ridge National Laboratory
Additional owner	Prof. Dr. Jochen Graw, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Developmental Genetics, Neuherberg/Germany
Genetic information	Unknown mutation. Dominant mutation, problems in penetrance observed. Mutation generated by N-ethyl-N-nitrosourea (ENU) Disclaimer - Special restrictions: 1) Mutant development was phenotype driven. Although for some mutant lines, linkage data and the molecular characterization of the causative mutation has been published, EMMA has not genotyped the strains and can not provide genotyping protocols. 2) Some lines showed low penetrance of the phenotype. 3) Only sperm available. Rederivation service can not be offered. 4) EMMA quality control standards may not apply for these strains. 5) EMMA has not verified the breeding performance and the genetic background of the strains. The genotype/phenotype of the mice is not confirmed by INFRAFRONTIER/EMMA. We strongly recommend that the recipient confirms genotype/phenotype upon receipt.
Phenotypic information	Homozygous: Not known whether homozygous mutants exist Heterozygous: Dominant mutation with incomplete (very roughly 50%) penetrance and much variation in expressivity. Anterior synechiae are present; sometimes the iris tissue will extend entirely across the dilated pupil and bisect it. The mutation often causes central lens opacities.
Breeding history	Kept as heterozygotes
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	not known
Immunocompromised	not known

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.