C57BL/6J-Vcanem1H/H

Status

Available to order

EMMA IDEM:12536
Citation informationRRID:IMSR_EM:12536 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6J-Vcanem1H/H
Alternative nameVCAN-E441A-EM1-B6
Strain typeEndonuclease-mediated
Allele/Transgene symbolVcanem1H
Gene/Transgene symbolVcan

Information from provider

Provider MRC-Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
Not known

Heterozygous:
None reported
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertileyes
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • abnormal heart morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal eye morphology / IMPC
  • abnormal heart looping / IMPC
  • microphthalmia / IMPC
  • prenatal lethality prior to heart atrial septation / IMPC
  • persistence of hyaloid vascular system / IMPC
  • abnormal embryo turning / IMPC
  • abnormal pharyngeal arch morphology / IMPC
  • abnormal vitelline vasculature morphology / IMPC
  • abnormal placenta morphology / IMPC
  • abnormal visceral yolk sac morphology / IMPC
  • abnormal spleen morphology / IMPC
  • decreased locomotor activity / IMPC
  • eye hemorrhage / IMPC
  • abnormal optic vesicle formation / IMPC
  • embryonic growth retardation / IMPC
  • preweaning lethality, complete penetrance / IMPC
  • abnormal neural tube morphology / IMPC
  • abnormal somite shape / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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