C57BL/6NTac-Atp13a3em2H/H

Status

Available to order

EMMA IDEM:12528
International strain nameC57BL/6NTac-Atp13a3em2H/H
Alternative nameATP13A3-P452LFS-EM2-B6N
Strain typeEndonuclease-mediated
Allele/Transgene symbolAtp13A3em2H
Gene/Transgene symbolAtp13a3

Information from provider

Provider MRC-Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
Not known

Heterozygous:
None reported
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertileyes
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • improved glucose tolerance / IMPC
  • increased bone mineral content / IMPC
  • decreased locomotor activity / IMPC
  • increased erythrocyte cell number / IMPC
  • decreased fasting circulating glucose level / IMPC
  • increased heart weight / IMPC
  • decreased circulating total protein level / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased anxiety-related response / IMPC
  • decreased circulating cholesterol level / IMPC
  • decreased exploration in new environment / IMPC
  • male infertility / IMPC
  • increased leukocyte cell number / IMPC
  • thrombocytopenia / IMPC
  • decreased blood urea nitrogen level / IMPC
  • decreased circulating HDL cholesterol level / IMPC
  • increased circulating bilirubin level / IMPC
  • decreased circulating triglyceride level / IMPC
  • decreased circulating serum albumin level / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased hematocrit / IMPC
  • abnormal cholesterol homeostasis / IMPC
  • decreased mean corpuscular volume / IMPC
  • decreased circulating glucose level / IMPC
  • abnormal skin coloration / IMPC
  • decreased mean corpuscular hemoglobin / IMPC
  • abnormal retina blood vessel morphology / IMPC
  • increased circulating alanine transaminase level / IMPC
  • increased startle reflex / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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