- increased leukocyte cell number / IMPC
- increased neutrophil cell number / IMPC
- abnormal coat/ hair morphology / IMPC
- abnormal spleen morphology / IMPC
- small testis / IMPC
- female infertility / IMPC
- abnormal seminal vesicle morphology / IMPC
- abnormal coat/hair pigmentation / IMPC
- increased circulating alanine transaminase level / IMPC
- increased lymphocyte cell number / IMPC
- increased bone mineral content / IMPC
C57BL/6NTac-Bnc1em1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:12501 |
International strain name | C57BL/6NTac-Bnc1em1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Bnc1em1(IMPC)H |
Gene/Transgene symbol | Bnc1 |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- 46,XX gonadal dysgenesis / Orphanet_243
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- small testis / IMPC
- abnormal spleen morphology / IMPC
- female infertility / IMPC
- increased bone mineral content / IMPC
- abnormal coat/hair pigmentation / IMPC
- increased leukocyte cell number / IMPC
- increased lymphocyte cell number / IMPC
- abnormal coat/ hair morphology / IMPC
- abnormal seminal vesicle morphology / IMPC
- increased circulating alanine transaminase level / IMPC
- increased neutrophil cell number / IMPC
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