C57BL/6NCrl-Fgf20em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12495
International strain nameC57BL/6NCrl-Fgf20em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFgf20em1(IMPC)Ccpcz
Gene/Transgene symbolFgf20

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal vertebrae morphology / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal stomach morphology / IMPC
  • abnormal autopod morphology / IMPC
  • abnormal nail morphology / IMPC
  • abnormal liver morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal uterus morphology / IMPC
  • corneal opacity / IMPC
  • abnormal startle reflex / IMPC
  • decreased startle reflex / IMPC
  • increased circulating HDL cholesterol level / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal kidney morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • small kidney / IMPC
  • abnormal bone structure / IMPC
  • enlarged stomach / IMPC
  • decreased kidney weight / IMPC
  • abnormal vertebral arch morphology / IMPC
  • vertebral fusion / IMPC
  • fusion of vertebral arches / IMPC
  • increased circulating cholesterol level / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased circulating total protein level / IMPC
  • decreased prepulse inhibition / IMPC
  • abnormal thoracic cage shape / IMPC
IMPC phenotypes (gene matching)
  • abnormal seminal vesicle morphology / IMPC
  • abnormal bone structure / IMPC
  • abnormal spleen morphology / IMPC
  • decreased kidney weight / IMPC
  • increased circulating cholesterol level / IMPC
  • fusion of vertebral arches / IMPC
  • vertebral fusion / IMPC
  • abnormal vertebral arch morphology / IMPC
  • increased circulating HDL cholesterol level / IMPC
  • abnormal vertebrae morphology / IMPC
  • increased blood urea nitrogen level / IMPC
  • small kidney / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal startle reflex / IMPC
  • abnormal kidney morphology / IMPC
  • increased circulating total protein level / IMPC
  • decreased prepulse inhibition / IMPC
  • abnormal digit morphology / IMPC
  • abnormal nail morphology / IMPC
  • abnormal stomach morphology / IMPC
  • abnormal uterus morphology / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • decreased startle reflex / IMPC
  • enlarged thymus / IMPC
  • enlarged spleen / IMPC
  • enlarged heart / IMPC
  • abnormal tooth morphology / IMPC
  • abnormal liver morphology / IMPC
  • abnormal heart morphology / IMPC
  • abnormal skin morphology / IMPC
  • corneal opacity / IMPC
  • abnormal thoracic cage shape / IMPC
  • enlarged stomach / IMPC
  • abnormal autopod morphology / IMPC

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

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