C57BL/6NTac-Gabra2em1(IMPC)H/H

Status

Available to order

EMMA IDEM:12467
International strain nameC57BL/6NTac-Gabra2em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGabra2em1(IMPC)H
Gene/Transgene symbolGabra2

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • corneal opacity / IMPC
  • increased anxiety-related response / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • decreased exploration in new environment / IMPC
  • trunk curl / IMPC
  • limb grasping / IMPC
  • increased thigmotaxis / IMPC
  • increased lean body mass / IMPC
  • abnormal behavior / IMPC
  • decreased heart rate / IMPC
  • decreased total body fat amount / IMPC
  • increased grip strength / IMPC
  • prolonged RR interval / IMPC
  • decreased fasting circulating glucose level / IMPC
IMPC phenotypes (gene matching)
  • hyperactivity / IMPC
  • decreased exploration in new environment / IMPC
  • trunk curl / IMPC
  • increased lean body mass / IMPC
  • corneal opacity / IMPC
  • limb grasping / IMPC
  • increased anxiety-related response / IMPC
  • decreased heart rate / IMPC
  • decreased locomotor activity / IMPC
  • increased grip strength / IMPC
  • prolonged RR interval / IMPC
  • decreased fasting circulating glucose level / IMPC
  • abnormal behavior / IMPC
  • decreased total body fat amount / IMPC
  • increased thigmotaxis / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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