C57BL/6NTac-Tpoem1(IMPC)H/H

Status

Available to order

EMMA IDEM:12441
International strain nameC57BL/6NTac-Tpoem1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolTpoem1(IMPC)H
Gene/Transgene symbolTpo

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal coat/ hair morphology / IMPC
  • abnormal forelimb morphology / IMPC
  • abnormal hindlimb morphology / IMPC
  • tremors / IMPC
  • abnormal gait / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal startle reflex / IMPC
  • limb grasping / IMPC
  • impaired righting response / IMPC
  • increased mean platelet volume / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased circulating cholesterol level / IMPC
  • improved glucose tolerance / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased circulating creatinine level / IMPC
  • decreased circulating glucose level / IMPC
  • increased circulating iron level / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
IMPC phenotypes (gene matching)
  • increased circulating aspartate transaminase level / IMPC
  • decreased circulating glucose level / IMPC
  • abnormal hindlimb morphology / IMPC
  • abnormal startle reflex / IMPC
  • abnormal coat/ hair morphology / IMPC
  • impaired righting response / IMPC
  • abnormal forelimb morphology / IMPC
  • abnormal gait / IMPC
  • tremors / IMPC
  • increased mean platelet volume / IMPC
  • increased circulating creatinine level / IMPC
  • improved glucose tolerance / IMPC
  • limb grasping / IMPC
  • decreased exploration in new environment / IMPC
  • increased circulating iron level / IMPC
  • increased circulating cholesterol level / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • preweaning lethality, incomplete penetrance / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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