C57BL/6NTac-Usp31em1(IMPC)H/H

Status

Available to order

EMMA IDEM:12431
International strain nameC57BL/6NTac-Usp31em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolUsp31em1(IMPC)H
Gene/Transgene symbolUsp31

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • tremors / IMPC
  • decreased locomotor activity / IMPC
  • abnormal gait / IMPC
  • decreased exploration in new environment / IMPC
  • decreased startle reflex / IMPC
  • increased lean body mass / IMPC
  • increased circulating potassium level / IMPC
  • impaired pupillary reflex / IMPC
  • decreased prepulse inhibition / IMPC
  • decreased total body fat amount / IMPC
IMPC phenotypes (gene matching)
  • increased eosinophil cell number / IMPC
  • increased prepulse inhibition / IMPC
  • increased circulating glucose level / IMPC
  • decreased locomotor activity / IMPC
  • decreased total body fat amount / IMPC
  • increased circulating phosphate level / IMPC
  • decreased exploration in new environment / IMPC
  • increased circulating creatinine level / IMPC
  • tremors / IMPC
  • decreased mean corpuscular volume / IMPC
  • decreased grip strength / IMPC
  • abnormal gait / IMPC
  • decreased startle reflex / IMPC
  • impaired pupillary reflex / IMPC
  • increased lean body mass / IMPC
  • decreased prepulse inhibition / IMPC
  • increased basophil cell number / IMPC
  • decreased hematocrit / IMPC
  • increased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating potassium level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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