STOCK Cfap157tm1d(EUCOMM)Hmgu/Biat
| Status | Available to order |
| EMMA ID | EM:12396 |
| International strain name | STOCK Cfap157tm1d(EUCOMM)Hmgu/Biat |
| Alternative name | Cfap157-delta-ex2 generated from Cfap157tm1a(EUCOMM)Hmgu |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Cfap157tm1d(EUCOMM)Hmgu |
| Gene/Transgene symbol | Cfap157 |
Information from provider
| Provider | Achim Gossler |
| Provider affiliation | MHH |
| Genetic information | cre recombinase-mediated germline deletion of exon 2, null allele |
| Phenotypic information | Homozygous:Immotile spermHeterozygous:No phenotype |
| Breeding history | Germ-line chimera bred to Tg(Zp3-cre) on a mixed genetic background (C57BL/6; 129Sv; CD1). Further breeding on this background. |
| References |
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| Homozygous fertile | females only |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous Other (please specify below) |
Literature references
- CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.;Weidemann Marina, Schuster-Gossler Karin, Stauber Michael, Wrede Christoph, Hegermann Jan, Ott Tim, Boldt Karsten, Beyer Tina, Serth Katrin, Kremmer Elisabeth, Blum Martin, Ueffing Marius, Gossler Achim, ;2016;Development (Cambridge, England);143;4736-4748; 27965440