C57BL/6NTac-Gria1em1(IMPC)H/H

Status

Available to order

EMMA IDEM:12371
Citation informationRRID:IMSR_EM:12371 

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International strain nameC57BL/6NTac-Gria1em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGria1em1(IMPC)H
Gene/Transgene symbolGria1

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal locomotor behavior / IMPC
  • hyperactivity / IMPC
  • abnormal gait / IMPC
  • decreased exploration in new environment / IMPC
  • increased circulating serum albumin level / IMPC
  • hypoalgesia / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased circulating iron level / IMPC
  • decreased prepulse inhibition / IMPC
  • impaired contextual conditioning behavior / IMPC
  • impaired cued conditioning behavior / IMPC
  • abnormal freezing behavior / IMPC
  • decreased freezing behavior / IMPC
  • increased mechanical nociceptive threshold / IMPC
IMPC phenotypes (gene matching)
  • hyperactivity / IMPC
  • increased circulating amylase level / IMPC
  • decreased freezing behavior / IMPC
  • decreased exploration in new environment / IMPC
  • increased circulating serum albumin level / IMPC
  • decreased prepulse inhibition / IMPC
  • increased blood urea nitrogen level / IMPC
  • impaired contextual conditioning behavior / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • abnormal freezing behavior / IMPC
  • abnormal gait / IMPC
  • impaired cued conditioning behavior / IMPC
  • increased circulating iron level / IMPC
  • increased mechanical nociceptive threshold / IMPC
  • abnormal locomotor behavior / IMPC
  • decreased bone mineral content / IMPC
  • decreased vertical activity / IMPC
  • hypoalgesia / IMPC
  • decreased startle reflex / IMPC
MGI phenotypes (gene matching)
  • abnormal spinal cord morphology / MGI
  • decreased body size / MGI
  • abnormal social investigation / MGI
  • increased anxiety-related response / MGI
  • decreased anxiety-related response / MGI
  • abnormal locomotor behavior / MGI
  • hyperactivity / MGI
  • abnormal response to new environment / MGI
  • increased exploration in new environment / MGI
  • reduced long term potentiation / MGI
  • absent long term depression / MGI
  • impaired synaptic plasticity / MGI
  • abnormal associative learning / MGI
  • no abnormal phenotype detected / MGI
  • abnormal long term potentiation / MGI
  • abnormal sexual interaction / MGI
  • abnormal emotion/affect behavior / MGI
  • increased vertical activity / MGI
  • abnormal nociception after inflammation / MGI
  • no phenotypic analysis / MGI
  • nervous system phenotype / MGI
  • decreased aggression towards males / MGI
  • abnormal serotonin level / MGI
  • homeostasis/metabolism phenotype / MGI
  • behavior/neurological phenotype / MGI
  • increased blood urea nitrogen level / MGI
  • decreased glycosylated hemoglobin level / MGI
  • abnormal dendrite morphology / MGI
  • abnormal long term spatial reference memory / MGI
  • decreased chemical nociceptive threshold / MGI
  • induced hyperactivity / MGI
  • abnormal behavioral response to xenobiotic / MGI
  • decreased behavioral withdrawal response / MGI
  • reduced AMPA-mediated synaptic currents / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
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Material Transfer Agreement (MTA)
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