C57BL/6NTac-Gpr146em1(IMPC)H/H

Status

Available to order

EMMA IDEM:12365
International strain nameC57BL/6NTac-Gpr146em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGpr146em1(IMPC)H
Gene/Transgene symbolGpr146

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased circulating HDL cholesterol level / IMPC
  • tremors / IMPC
  • decreased mean corpuscular volume / IMPC
  • decreased circulating triglyceride level / IMPC
  • decreased hemoglobin content / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased circulating iron level / IMPC
  • increased spleen weight / IMPC
  • decreased circulating cholesterol level / IMPC
  • thrombocytosis / IMPC
  • decreased mean corpuscular hemoglobin / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
  • increased red blood cell distribution width / IMPC
IMPC phenotypes (gene matching)
  • decreased circulating iron level / IMPC
  • tremors / IMPC
  • increased red blood cell distribution width / IMPC
  • decreased hemoglobin content / IMPC
  • decreased mean corpuscular volume / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased circulating cholesterol level / IMPC
  • decreased mean corpuscular hemoglobin / IMPC
  • increased spleen weight / IMPC
  • decreased circulating triglyceride level / IMPC
  • thrombocytosis / IMPC
  • decreased circulating HDL cholesterol level / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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