C57BL/6NTac-Them1(IMPC)H/H
Status | Available to order |
EMMA ID | EM:12361 |
Citation information | RRID:IMSR_EM:12361 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NTac-Them1(IMPC)H/H |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Them1(IMPC)H |
Gene/Transgene symbol | Th |
Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- vasculature congestion / MGI
- abnormal heart development / MGI
- ventricular hypoplasia / MGI
- weakness / MGI
- atelectasis / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal cued conditioning behavior / MGI
- abnormal motor coordination/balance / MGI
- respiratory failure / MGI
- abnormal associative learning / MGI
- abnormal learning/memory/conditioning / MGI
- no abnormal phenotype detected / MGI
- anoxia / MGI
- abnormal active avoidance behavior / MGI
- abnormal conditioned taste aversion behavior / MGI
- no phenotypic analysis / MGI
- abnormal heart atrium morphology / MGI
- dilated heart atrium / MGI
- abnormal ST segment / MGI
- abnormal adrenaline level / MGI
- abnormal noradrenaline level / MGI
- bradykinesia / MGI
- decreased heart rate / MGI
- decreased dopamine level / MGI
- abnormal fetal cardiomyocyte morphology / MGI
- visceral vascular congestion / MGI
- liver vascular congestion / MGI
- heart vascular congestion / MGI
- increased serotonin level / MGI
- postnatal lethality, complete penetrance / MGI
- neonatal lethality, complete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- decreased noradrenaline level / MGI
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