C57BL/6NCrl-Sox14em1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:12279
Citation informationRRID:IMSR_EM:12279 

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International strain nameC57BL/6NCrl-Sox14em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSox14em1(IMPC)Ccpcz
Gene/Transgene symbolSox14

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl males

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal snout morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • small seminal vesicle / IMPC
  • decreased body weight / IMPC
  • microphthalmia / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • abnormal gait / IMPC
  • decreased startle reflex / IMPC
  • trunk curl / IMPC
  • limb grasping / IMPC
  • abnormal vocalization / IMPC
  • male infertility / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal eye morphology / IMPC
  • small heart / IMPC
  • abnormal lymph node morphology / IMPC
  • small kidney / IMPC
  • abnormal auditory brainstem response / IMPC
  • abnormal behavior / IMPC
  • increased aggression / IMPC
  • increased prepulse inhibition / IMPC
  • increased grip strength / IMPC
  • decreased respiratory quotient / IMPC
  • increased airway resistance / IMPC
  • increased lung tissue damping / IMPC
  • increased freezing behavior / IMPC
  • decreased thigmotaxis / IMPC
IMPC phenotypes (gene matching)
  • increased freezing behavior / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal behavior / IMPC
  • decreased thigmotaxis / IMPC
  • increased prepulse inhibition / IMPC
  • enlarged thymus / IMPC
  • abnormal heart morphology / IMPC
  • decreased startle reflex / IMPC
  • trunk curl / IMPC
  • microphthalmia / IMPC
  • hyperactivity / IMPC
  • abnormal auditory brainstem response / IMPC
  • small kidney / IMPC
  • abnormal gait / IMPC
  • decreased body weight / IMPC
  • increased lung tissue damping / IMPC
  • abnormal thymus morphology / IMPC
  • abnormal eye morphology / IMPC
  • enlarged heart / IMPC
  • increased aggression / IMPC
  • abnormal snout morphology / IMPC
  • increased airway resistance / IMPC
  • limb grasping / IMPC
  • decreased locomotor activity / IMPC
  • decreased respiratory quotient / IMPC
  • small heart / IMPC
  • enlarged lymph nodes / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • male infertility / IMPC
  • abnormal vocalization / IMPC
  • small seminal vesicle / IMPC
  • abnormal skin morphology / IMPC
  • increased grip strength / IMPC
MGI phenotypes (gene matching)
  • no phenotypic analysis / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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