- abnormal heart morphology / IMPC
- enlarged heart / IMPC
- abnormal snout morphology / IMPC
- abnormal spleen morphology / IMPC
- enlarged lymph nodes / IMPC
- abnormal thymus morphology / IMPC
- enlarged thymus / IMPC
- small seminal vesicle / IMPC
- decreased body weight / IMPC
- microphthalmia / IMPC
- hyperactivity / IMPC
- decreased locomotor activity / IMPC
- abnormal gait / IMPC
- decreased startle reflex / IMPC
- trunk curl / IMPC
- limb grasping / IMPC
- abnormal vocalization / IMPC
- male infertility / IMPC
- abnormal seminal vesicle morphology / IMPC
- abnormal skin morphology / IMPC
- abnormal eye morphology / IMPC
- small heart / IMPC
- abnormal lymph node morphology / IMPC
- small kidney / IMPC
- abnormal auditory brainstem response / IMPC
- abnormal behavior / IMPC
- increased aggression / IMPC
- increased prepulse inhibition / IMPC
- increased grip strength / IMPC
- decreased respiratory quotient / IMPC
- increased airway resistance / IMPC
- increased lung tissue damping / IMPC
- increased freezing behavior / IMPC
- decreased thigmotaxis / IMPC
C57BL/6NCrl-Sox14em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12279 |
International strain name | C57BL/6NCrl-Sox14em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Sox14em1(IMPC)Ccpcz |
Gene/Transgene symbol | Sox14 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased freezing behavior / IMPC
- abnormal spleen morphology / IMPC
- abnormal behavior / IMPC
- decreased thigmotaxis / IMPC
- increased prepulse inhibition / IMPC
- enlarged thymus / IMPC
- abnormal heart morphology / IMPC
- decreased startle reflex / IMPC
- trunk curl / IMPC
- microphthalmia / IMPC
- hyperactivity / IMPC
- abnormal auditory brainstem response / IMPC
- small kidney / IMPC
- abnormal gait / IMPC
- decreased body weight / IMPC
- increased lung tissue damping / IMPC
- abnormal thymus morphology / IMPC
- abnormal eye morphology / IMPC
- enlarged heart / IMPC
- increased aggression / IMPC
- abnormal snout morphology / IMPC
- increased airway resistance / IMPC
- limb grasping / IMPC
- decreased locomotor activity / IMPC
- decreased respiratory quotient / IMPC
- small heart / IMPC
- enlarged lymph nodes / IMPC
- abnormal seminal vesicle morphology / IMPC
- abnormal lymph node morphology / IMPC
- male infertility / IMPC
- abnormal vocalization / IMPC
- small seminal vesicle / IMPC
- abnormal skin morphology / IMPC
- increased grip strength / IMPC
MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
Information on how we integrate external resources can be found here
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