C57BL/6NCrl-Crxem1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:12278
Citation informationRRID:IMSR_EM:12278 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Crxem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolCrxem1(IMPC)Ccpcz
Gene/Transgene symbolCrx

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal urinary bladder morphology / IMPC
  • abnormal thymus morphology / IMPC
  • small thymus / IMPC
  • enlarged thymus / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • abnormal retina morphology / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal skin morphology / IMPC
  • short tibia / IMPC
  • increased NK cell number / IMPC
  • enlarged urinary bladder / IMPC
  • increased fasting circulating glucose level / IMPC
IMPC phenotypes (gene matching)
  • enlarged thymus / IMPC
  • increased fasting circulating glucose level / IMPC
  • enlarged heart / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged urinary bladder / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • abnormal heart morphology / IMPC
  • abnormal urinary bladder morphology / IMPC
  • abnormal skin morphology / IMPC
  • increased NK cell number / IMPC
  • abnormal retina morphology / IMPC
  • short tibia / IMPC
  • small thymus / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal seminal vesicle morphology / IMPC
MGI phenotypes (gene matching)
  • abnormal retinal photoreceptor morphology / MGI
  • abnormal retinal cone cell morphology / MGI
  • abnormal retina morphology / MGI
  • blindness / MGI
  • abnormal blood circulation / MGI
  • abnormal ocular fundus morphology / MGI
  • abnormal retinal layer morphology / MGI
  • abnormal retinal photoreceptor layer morphology / MGI
  • abnormal photoreceptor outer segment morphology / MGI
  • abnormal photoreceptor inner segment morphology / MGI
  • abnormal retinal outer nuclear layer morphology / MGI
  • abnormal retinal outer plexiform layer morphology / MGI
  • abnormal rod electrophysiology / MGI
  • abnormal cone electrophysiology / MGI
  • abnormal retinal pigmentation / MGI
  • vision/eye phenotype / MGI
  • abnormal eye electrophysiology / MGI
  • abnormal horizontal cell morphology / MGI
  • abnormal retinal bipolar cell morphology / MGI
  • abnormal retinal rod bipolar cell morphology / MGI
  • abnormal retinal cone bipolar cell morphology / MGI
  • decreased retinal cone cell number / MGI
  • retinal photoreceptor degeneration / MGI
  • abnormal retinal rod cell outer segment morphology / MGI
  • thin retinal outer nuclear layer / MGI
  • retinal outer nuclear layer degeneration / MGI
  • thin retinal outer plexiform layer / MGI
  • short photoreceptor inner segment / MGI
  • absent photoreceptor inner segment / MGI
  • absent photoreceptor outer segment / MGI
  • abnormal retinal blood vessel morphology / MGI
  • abnormal retinal outer nuclear layer thickness / MGI
  • abnormal electroretinogram waveform feature / MGI
  • decreased a wave amplitude / MGI
  • decreased b wave amplitude / MGI
  • retinal spots / MGI
  • abnormal circadian behavior / MGI
  • delayed circadian behavior phase / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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