C57BL/6NCrl-Asb7em1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:12241
International strain nameC57BL/6NCrl-Asb7em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolAsb7em1(IMPC)Ccpcz
Gene/Transgene symbolAsb7

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl

Disease and phenotype information

IMPC phenotypes (allele matching)
  • decreased leukocyte cell number / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal uterus morphology / IMPC
  • anophthalmia / IMPC
  • decreased locomotor activity / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal skin morphology / IMPC
  • abnormal eye morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • increased kidney weight / IMPC
  • enlarged uterus / IMPC
  • decreased lymphocyte cell number / IMPC
  • increased cardiac muscle contractility / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC
  • enhanced cued conditioning behavior / IMPC
  • decreased grip strength / IMPC
  • dilated aorta / IMPC
  • increased fasting circulating glucose level / IMPC
IMPC phenotypes (gene matching)
  • decreased lymphocyte cell number / IMPC
  • decreased grip strength / IMPC
  • increased fasting circulating glucose level / IMPC
  • abnormal heart morphology / IMPC
  • abnormal eye morphology / IMPC
  • increased circulating alkaline phosphatase level / IMPC
  • anophthalmia / IMPC
  • enlarged heart / IMPC
  • abnormal spleen morphology / IMPC
  • decreased locomotor activity / IMPC
  • abnormal uterus morphology / IMPC
  • increased cardiac muscle contractility / IMPC
  • enlarged spleen / IMPC
  • dilated aorta / IMPC
  • decreased exploration in new environment / IMPC
  • decreased leukocyte cell number / IMPC
  • abnormal skin morphology / IMPC
  • enhanced cued conditioning behavior / IMPC
  • increased kidney weight / IMPC
  • enlarged uterus / IMPC
  • decreased CD8-positive, alpha-beta T cell number / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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