C57BL/6NCrl-Birc6em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12236 |
International strain name | C57BL/6NCrl-Birc6em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Birc6em1(IMPC)Ccpcz |
Gene/Transgene symbol | Birc6 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- abnormal angiogenesis / MGI
- decreased cell proliferation / MGI
- decreased hepatocyte number / MGI
- abnormal placenta morphology / MGI
- abnormal placenta labyrinth morphology / MGI
- edema / MGI
- hemorrhage / MGI
- intraventricular hemorrhage / MGI
- abnormal definitive hematopoiesis / MGI
- no abnormal phenotype detected / MGI
- abnormal cell cycle / MGI
- abnormal placenta vasculature / MGI
- abnormal embryonic hematopoiesis / MGI
- pallor / MGI
- decreased fetal size / MGI
- fetal growth retardation / MGI
- abnormal spongiotrophoblast layer morphology / MGI
- small placenta / MGI
- abnormal trophoblast layer morphology / MGI
- embryonic lethality / MGI
- abnormal placental labyrinth vasculature morphology / MGI
- increased thymocyte apoptosis / MGI
- neonatal lethality, complete penetrance / MGI
- perinatal lethality, complete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- increased fibroblast apoptosis / MGI
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