B6;D2-Tg(St18-cre/ERT2)1Ffr/Orl
| Status | Available to order |
| EMMA ID | EM:12206 |
| Citation information | RRID:IMSR_EM:12206 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;D2-Tg(St18-cre/ERT2)1Ffr/Orl |
| Alternative name | Tg St18-CreERT2 C57BL/6J |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(St18-cre/ERT2)1Ffr |
| Gene/Transgene symbol | Tg(St18-cre/ERT2)1Ffr |
Information from provider
| Provider | Fiona Francis |
| Provider affiliation | Institut du Fer à Moulin, Inserm UMR-S 839 |
| Genetic information | Transgenic line produced by classical transgenesis (microinjection into B6D2F2 (B6D2F1 x B6D2F1)) using a modified BAC clone (RPCI-23-2303) containing the "suppression of tumorigenicity 18" (St18) gene. BAC recombining was used to insert the CreERT2 FRT Neo FRT cassette by homologous recombination into the genomic St18 locus. |
| Phenotypic information | Homozygous:Not yet tested but likely to be normal.Heterozygous:Normal. No obvious phenotype detected. Mice are viable and fertile. These mice have been crossed with a reporter line and the CreERT2 expression (induced by tamoxifen) faithfully mimics the St18 in situ hybridisation result. We wish to deposit this heterozygote line in EMMA. |
| Breeding history | A Tg St18-CreERT2 male founder was crossed with wild-type C57BL/6J females to generate 5 heterozygote offspring (of 8 born in July 2018) (two males, three females). Females are being re-crossed with wild type C57BL/6J mice. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males |