C57BL/6NCrl-Cul9em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:12185
Citation informationRRID:IMSR_EM:12185 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Cul9em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolCul9em1(IMPC)Ccpcz
Gene/Transgene symbolCul9

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal vertebrae morphology / IMPC
  • abnormal spleen morphology / IMPC
  • enlarged spleen / IMPC
  • abnormal thymus morphology / IMPC
  • enlarged thymus / IMPC
  • abnormal kidney morphology / IMPC
  • vertebral transformation / IMPC
  • abnormal vertebral arch morphology / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased circulating potassium level / IMPC
  • increased circulating creatine kinase level / IMPC
  • increased circulating lactate dehydrogenase level / IMPC
IMPC phenotypes (gene matching)
  • vertebral transformation / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal kidney morphology / IMPC
  • increased circulating lactate dehydrogenase level / IMPC
  • abnormal vertebral arch morphology / IMPC
  • increased circulating creatine kinase level / IMPC
  • enlarged spleen / IMPC
  • enlarged thymus / IMPC
  • increased circulating potassium level / IMPC
  • abnormal vertebrae morphology / IMPC
  • increased blood urea nitrogen level / IMPC
  • abnormal thymus morphology / IMPC
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • increased tumor incidence / MGI
  • increased sarcoma incidence / MGI
  • premature death / MGI
  • no abnormal phenotype detected / MGI
  • no phenotypic analysis / MGI
  • decreased cellular sensitivity to gamma-irradiation / MGI
  • increased insulinoma incidence / MGI
  • increased incidence of tumors by chemical induction / MGI
  • cellular phenotype / MGI
  • increased ovary tumor incidence / MGI
  • increased lung tumor incidence / MGI
  • increased liver tumor incidence / MGI
  • decreased cellular sensitivity to ultraviolet irradiation / MGI
  • increased pituitary gland tumor incidence / MGI
  • increased lymphoma incidence / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

    Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

    * In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

    More details on pricing and delivery times

    Practical information

    Example health report
    (Current health report will be provided later)

    Material Transfer Agreement (MTA)
    Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

    EMMA conditions
    Legally binding conditions for the transfer

    Other EMMA strains

    Not found what you were looking for? Search here for other strains available from EMMA.


    Search
    INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).