- abnormal liver morphology / IMPC
- tremors / IMPC
- abnormal testis morphology / IMPC
- small testis / IMPC
- decreased anxiety-related response / IMPC
- abnormal locomotor behavior / IMPC
- hyperactivity / IMPC
- increased exploration in new environment / IMPC
- increased circulating alkaline phosphatase level / IMPC
- decreased grip strength / IMPC
- increased fasting circulating glucose level / IMPC
C57BL/6NCrl-Tmem240em1(IMPC)Ccpcz/Ph
Status | Available to order |
EMMA ID | EM:12176 |
International strain name | C57BL/6NCrl-Tmem240em1(IMPC)Ccpcz/Ph |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Tmem240em1(IMPC)Ccpcz |
Gene/Transgene symbol | Tmem240 |
Information from provider
Provider | Institute of Molecular Genetics |
Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Animals used for archiving | heterozygous C57BL/6NCrl |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Spinocerebellar ataxia type 21 / Orphanet_98773
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal testis morphology / IMPC
- hyperactivity / IMPC
- decreased grip strength / IMPC
- increased exploration in new environment / IMPC
- increased fasting circulating glucose level / IMPC
- decreased anxiety-related response / IMPC
- increased circulating alkaline phosphatase level / IMPC
- abnormal locomotor behavior / IMPC
- tremors / IMPC
- small testis / IMPC
- abnormal liver morphology / IMPC
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