C57BL/6NCrl-Fam83hem1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:12171
International strain nameC57BL/6NCrl-Fam83hem1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolFam83hem1(IMPC)Ccpcz
Gene/Transgene symbolFam83h

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal heart morphology / IMPC
  • abnormal coat/ hair morphology / IMPC
  • abnormal mammary gland morphology / IMPC
  • abnormal testis morphology / IMPC
  • small testis / IMPC
  • decreased locomotor activity / IMPC
  • no spontaneous movement / IMPC
  • decreased exploration in new environment / IMPC
  • abnormal coat appearance / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal kidney morphology / IMPC
  • small heart / IMPC
  • abnormal behavior / IMPC
  • abnormal gallbladder morphology / IMPC
  • abnormal cholesterol homeostasis / IMPC
  • increased circulating potassium level / IMPC
  • decreased grip strength / IMPC
  • increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
IMPC phenotypes (gene matching)
  • decreased exploration in new environment / IMPC
  • abnormal coat appearance / IMPC
  • abnormal cholesterol homeostasis / IMPC
  • abnormal testis morphology / IMPC
  • no spontaneous movement / IMPC
  • abnormal heart morphology / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • abnormal coat/ hair morphology / IMPC
  • abnormal kidney morphology / IMPC
  • small testis / IMPC
  • increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number / IMPC
  • decreased grip strength / IMPC
  • decreased locomotor activity / IMPC
  • increased circulating potassium level / IMPC
  • small heart / IMPC
  • abnormal behavior / IMPC
  • abnormal mammary gland morphology / IMPC
  • abnormal seminal vesicle morphology / IMPC
  • abnormal gallbladder morphology / IMPC
MGI phenotypes (gene matching)
  • sparse hair / MGI
  • weakness / MGI
  • scaly skin / MGI
  • decreased body size / MGI
  • hypoactivity / MGI
  • disheveled coat / MGI
  • premature death / MGI
  • delayed tooth eruption / MGI
  • craniofacial phenotype / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • abnormal oral cavity morphology / MGI
  • periodontal pocket / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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