IMPC phenotypes (allele matching)
STOCK Dusp1tm1(KOMP)Wtsi/Wtsi
| Status | Available to order |
| EMMA ID | EM:12065 |
| International strain name | STOCK Dusp1tm1(KOMP)Wtsi/Wtsi |
| Alternative name | EPD0272_4_C01 |
| Strain type | |
| Allele/Transgene symbol | Dusp1tm1(KOMP)Wtsi |
| Gene/Transgene symbol | Dusp1 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from KOMP ES clone EPD0272_4_C01. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Wellcome Trust Sanger Institute, Hinxton, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6N |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased granulocyte number / MGI
- small liver / MGI
- abnormal myogenesis / MGI
- abnormal muscle development / MGI
- abnormal muscle regeneration / MGI
- abnormal superior cervical ganglion morphology / MGI
- thick pulmonary interalveolar septum / MGI
- decreased body weight / MGI
- weight loss / MGI
- decreased anxiety-related response / MGI
- abnormal eating behavior / MGI
- abnormal circulating alanine transaminase level / MGI
- hypotension / MGI
- lung inflammation / MGI
- decreased susceptibility to hepatic steatosis / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal innate immunity / MGI
- decreased circulating triglyceride level / MGI
- decreased circulating free fatty acid level / MGI
- decreased circulating alanine transaminase level / MGI
- abnormal cytokine secretion / MGI
- increased neuron apoptosis / MGI
- decreased susceptibility to age related obesity / MGI
- abnormal locomotor activation / MGI
- abnormal depression-related behavior / MGI
- abnormal gluconeogenesis / MGI
- decreased liver weight / MGI
- increased susceptibility to induced arthritis / MGI
- pulmonary edema / MGI
- abnormal nitric oxide homeostasis / MGI
- increased energy expenditure / MGI
- decreased circulating cholesterol level / MGI
- homeostasis/metabolism phenotype / MGI
- immune system phenotype / MGI
- decreased body temperature / MGI
- increased blood urea nitrogen level / MGI
- increased susceptibility to type I hypersensitivity reaction / MGI
- decreased susceptibility to diet-induced obesity / MGI
- decreased systemic arterial systolic blood pressure / MGI
- abnormal dendrite morphology / MGI
- increased circulating tumor necrosis factor level / MGI
- increased tumor necrosis factor secretion / MGI
- increased circulating interferon-gamma level / MGI
- increased circulating interleukin-10 level / MGI
- increased circulating interleukin-6 level / MGI
- increased interleukin-1 beta secretion / MGI
- increased interleukin-6 secretion / MGI
- abnormal chemokine level / MGI
- abnormal chemokine secretion / MGI
- increased susceptibility to endotoxin shock / MGI
- abnormal interleukin level / MGI
- increased mast cell degranulation / MGI
- decreased fat cell size / MGI
- decreased abdominal fat pad weight / MGI
- decreased epididymal fat pad weight / MGI
- decreased skeletal muscle fiber size / MGI
- decreased skeletal muscle fiber diameter / MGI
- increased sensitivity to induced morbidity/mortality / MGI
- increased sensitivity to xenobiotic induced morbidity/mortality / MGI
- increased prostaglandin level / MGI
- decreased total body fat amount / MGI
- increased respiratory quotient / MGI
- abnormal cellular respiration / MGI