IMPC phenotypes (allele matching)
STOCK Dusp1tm1(KOMP)Wtsi/Wtsi
| Status | Available to order |
| EMMA ID | EM:12065 |
| Citation information | RRID:IMSR_EM:12065 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Dusp1tm1(KOMP)Wtsi/Wtsi |
| Alternative name | EPD0272_4_C01 |
| Strain type | |
| Allele/Transgene symbol | Dusp1tm1(KOMP)Wtsi |
| Gene/Transgene symbol | Dusp1 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from KOMP ES clone EPD0272_4_C01. For further details on the construction of this clone see the page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Wellcome Trust Sanger Institute, Hinxton, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6N males |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased granulocyte number / MGI
- small liver / MGI
- abnormal myogenesis / MGI
- abnormal muscle development / MGI
- abnormal muscle regeneration / MGI
- abnormal superior cervical ganglion morphology / MGI
- thick pulmonary interalveolar septum / MGI
- decreased body weight / MGI
- weight loss / MGI
- decreased anxiety-related response / MGI
- abnormal eating behavior / MGI
- abnormal circulating alanine transaminase level / MGI
- hypotension / MGI
- lung inflammation / MGI
- decreased susceptibility to hepatic steatosis / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal innate immunity / MGI
- decreased circulating triglyceride level / MGI
- decreased circulating free fatty acid level / MGI
- decreased circulating alanine transaminase level / MGI
- abnormal cytokine secretion / MGI
- increased neuron apoptosis / MGI
- decreased susceptibility to age related obesity / MGI
- abnormal locomotor activation / MGI
- abnormal depression-related behavior / MGI
- abnormal gluconeogenesis / MGI
- decreased liver weight / MGI
- increased susceptibility to induced arthritis / MGI
- pulmonary edema / MGI
- abnormal nitric oxide homeostasis / MGI
- increased energy expenditure / MGI
- decreased circulating cholesterol level / MGI
- homeostasis/metabolism phenotype / MGI
- immune system phenotype / MGI
- decreased body temperature / MGI
- increased blood urea nitrogen level / MGI
- increased susceptibility to type I hypersensitivity reaction / MGI
- decreased susceptibility to diet-induced obesity / MGI
- decreased systemic arterial systolic blood pressure / MGI
- abnormal dendrite morphology / MGI
- increased circulating tumor necrosis factor level / MGI
- increased tumor necrosis factor secretion / MGI
- increased circulating interferon-gamma level / MGI
- increased circulating interleukin-10 level / MGI
- increased circulating interleukin-6 level / MGI
- increased interleukin-1 beta secretion / MGI
- increased interleukin-6 secretion / MGI
- abnormal chemokine level / MGI
- abnormal chemokine secretion / MGI
- increased susceptibility to endotoxin shock / MGI
- abnormal interleukin level / MGI
- increased mast cell degranulation / MGI
- decreased fat cell size / MGI
- decreased abdominal fat pad weight / MGI
- decreased epididymal fat pad weight / MGI
- decreased skeletal muscle fiber size / MGI
- decreased skeletal muscle fiber diameter / MGI
- increased sensitivity to induced morbidity/mortality / MGI
- increased sensitivity to xenobiotic induced morbidity/mortality / MGI
- increased prostaglandin level / MGI
- decreased total body fat amount / MGI
- increased respiratory quotient / MGI
- abnormal cellular respiration / MGI