B6(Cg)-Tg(Th-tTA2syn)1Ekra/H
| Status | Available to order |
| EMMA ID | EM:11952 |
| Citation information | RRID:IMSR_EM:11952 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6(Cg)-Tg(Th-tTA2syn)1Ekra/H |
| Alternative name | C57BL/6J-Tg(TH-tTA2syn)1EKra |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Unknown at present |
| Gene/Transgene symbol | TH-tTA |
Information from provider
| Provider | Edgar Kramer |
| Provider affiliation | Biomedical Research, Institute of Translational and Stratified Medicine, Peninsula Schools of Medicine and Dentistry, University of Plymouth |
| Genetic information | tTA2syn under the control of the mouse Th promoter (8.9kbp). |
| Phenotypic information | Homozygous:not doneHeterozygous:mTH-tTA OFF#2096 can be used to induced tTA expression in catecholaminergic neurons expressing tyrosine hydroxylase; tTA can induce gene expression in the absence of tetracycline/doxycycline (Tillack et al., 2015). |
| Breeding history | Crossed with LC1 mice (Schoenig et al., 2002), ROSA26R mice (Soriano, 1999) and Ret floxed mice (Kramer et al., 2006). |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |