C57BL/6NCrl-Insig1em1(IMPC)Ccpcz/Ph

Status

Available to order

EMMA IDEM:11914
Citation informationRRID:IMSR_EM:11914 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Insig1em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolInsig1em1(IMPC)Ccpcz
Gene/Transgene symbolInsig1

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingheterozygous C57BL/6NCrl males

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal maxilla morphology / IMPC
  • abnormal urinary bladder morphology / IMPC
  • decreased body weight / IMPC
  • decreased locomotor activity / IMPC
  • decreased circulating chloride level / IMPC
  • abnormal cholesterol homeostasis / IMPC
  • impaired glucose tolerance / IMPC
  • increased mean corpuscular hemoglobin / IMPC
  • decreased circulating sodium level / IMPC
  • increased aggression / IMPC
  • increased fasting circulating glucose level / IMPC
  • increased freezing behavior / IMPC
IMPC phenotypes (gene matching)
  • increased mean corpuscular hemoglobin / IMPC
  • decreased body weight / IMPC
  • impaired glucose tolerance / IMPC
  • increased aggression / IMPC
  • decreased circulating chloride level / IMPC
  • decreased circulating sodium level / IMPC
  • abnormal cholesterol homeostasis / IMPC
  • abnormal urinary bladder morphology / IMPC
  • abnormal maxilla morphology / IMPC
  • increased freezing behavior / IMPC
  • decreased locomotor activity / IMPC
  • increased fasting circulating glucose level / IMPC
MGI phenotypes (gene matching)
  • decreased body length / MGI
  • decreased body weight / MGI
  • decreased circulating triglyceride level / MGI
  • homeostasis/metabolism phenotype / MGI
  • behavior/neurological phenotype / MGI
  • abnormal white fat cell morphology / MGI
  • increased gonadal fat pad weight / MGI
  • increased subcutaneous adipose tissue amount / MGI
  • abnormal white fat cell differentation / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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