B6.129-Calb1tm2.1Mpin/Biat

Status

Available to order

EMMA IDEM:11899
Citation informationRRID:IMSR_EM:11899 

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International strain nameB6.129-Calb1tm2.1Mpin/Biat
Alternative nameB6.(R1)-Calb1
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolCalb1tm2.1Mpin
Gene/Transgene symbolCalb1

Information from provider

ProviderMichael Meyer
Provider affiliationPhysiology, Biomedical Center LMU München
Genetic informationThe strain is a conditional inactivation of the Calb1 gene (see EM:09881, B6.129-Calb1tm1Mpin/JBiat). The targeting vector was obtained by inserting a single loxP site upstream and a floxed neo-TK cassette downstream of the first exon (Fig. 1a in PMID: 11857810 Barski et al. Genesis 2002).
Phenotypic informationHomozygous:
none (see PMID: 11857810 Barski et al. Genesis 2002)

Heterozygous:
none
References
  • Conditional inactivation of the calbindin D-28k (Calb1) gene by Cre/loxP-mediated recombination.;Barski Jaroslaw J, Mörl Karin, Meyer Michael, ;2002;Genesis (New York, N.Y. : 2000);32;165-8; 11857810
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreUniversity of Veterinary Medicine, Vienna, Austria
Animals used for archivingheterozygous C57BL/6N males

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal thymus morphology / IMPC
  • abnormal vertebrae morphology / IMPC
  • abnormal testis morphology / IMPC
  • abnormal vertebral arch morphology / IMPC
  • hydrometra / IMPC
  • abnormal heart left ventricle morphology / IMPC
  • enlarged thymus / IMPC
  • small testis / IMPC
  • abnormal heart morphology / IMPC
  • enlarged heart / IMPC
  • abnormal spleen morphology / IMPC
  • small spleen / IMPC
  • enlarged spleen / IMPC
  • increased cardiac muscle contractility / IMPC
  • kyphosis / IMPC
  • abnormal retina morphology / IMPC
  • abnormal spine curvature / IMPC
  • abnormal uterus morphology / IMPC
MGI phenotypes (gene matching)
  • ataxia / MGI
  • no abnormal phenotype detected / MGI
  • abnormal nervous system electrophysiology / MGI
  • hearing/vestibular/ear phenotype / MGI
  • behavior/neurological phenotype / MGI

Literature references

  • Conditional inactivation of the calbindin D-28k (Calb1) gene by Cre/loxP-mediated recombination.;Barski Jaroslaw J, Mörl Karin, Meyer Michael, ;2002;Genesis (New York, N.Y. : 2000);32;165-8; 11857810

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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