IMPC phenotypes (allele matching)
C57BL/6N-Eml1em1(IMPC)Wtsi/WtsiH
| Status | Available to order |
| EMMA ID | EM:11887 |
| International strain name | C57BL/6N-Eml1em1(IMPC)Wtsi/WtsiH |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Eml1em1(IMPC)Wtsi |
| Gene/Transgene symbol | Eml1 |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Subcortical band heterotopia / Orphanet_99796
MGI phenotypes (gene matching)
- myoclonus / MGI
- delayed hair appearance / MGI
- abnormal cranium morphology / MGI
- thickened cerebral cortex / MGI
- decreased body weight / MGI
- decreased body size / MGI
- delayed eyelid opening / MGI
- abnormal locomotor behavior / MGI
- hypoactivity / MGI
- seizures / MGI
- altered righting response / MGI
- increased susceptibility to pharmacologically induced seizures / MGI
- abnormal locomotor activation / MGI
- nervous system phenotype / MGI
- bradykinesia / MGI
- abnormal cortical intermediate zone morphology / MGI
- enlarged brain ventricles / MGI
- ectopic cortical neuron / MGI
- impaired spatial learning / MGI
- brain atrophy / MGI