B6;D2-Tg(Ntrk2-cre/ERT2)#Phep/Cnrm

Status

Available to order

EMMA IDEM:11775
International strain nameB6;D2-Tg(Ntrk2-cre/ERT2)#Phep/Cnrm
Alternative nameTrkB-CreERT2
Strain typeTransgenic Strains
Allele/Transgene symbolTg(Ntrk2-cre/ERT2)#Phep
Gene/Transgene symbolTg(Ntrk2-cre/ERT2)#Phep

Information from provider

ProviderPaul Heppenstall
Provider affiliationEMBL
Genetic informationBacterial artificial chromosome (BAC) containing the TrkB mouse locus. A cassette containing a modified CreERT2-pA-Frt-Ampicillin-Frt construct was inserted into the ATG of BAC-TrkB, deleting entire coding part of exon 2 to avoid overexpression of TrkB.
Phenotypic informationHomozygous:
No overt phenotype

Heterozygous:
No overt phenotype
References
  • Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.;Dhandapani Rahul, Arokiaraj Cynthia Mary, Taberner Francisco J, Pacifico Paola, Raja Sruthi, Nocchi Linda, Portulano Carla, Franciosa Federica, Maffei Mariano, Hussain Ahmad Fawzi, de Castro Reis Fernanda, Reymond Luc, Perlas Emerald, Garcovich Simone, Barth Stefan, Johnsson Kai, Lechner Stefan G, Heppenstall Paul A, ;2018;Nature communications;9;1640; 29691410
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

  • Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.;Dhandapani Rahul, Arokiaraj Cynthia Mary, Taberner Francisco J, Pacifico Paola, Raja Sruthi, Nocchi Linda, Portulano Carla, Franciosa Federica, Maffei Mariano, Hussain Ahmad Fawzi, de Castro Reis Fernanda, Reymond Luc, Perlas Emerald, Garcovich Simone, Barth Stefan, Johnsson Kai, Lechner Stefan G, Heppenstall Paul A, ;2018;Nature communications;9;1640; 29691410

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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