C57BL/6NTac-Nrxn2em1(IMPC)H/H

Status

Available to order

EMMA IDEM:11733
International strain nameC57BL/6NTac-Nrxn2em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNrxn2em1(IMPC)H
Gene/Transgene symbolNrxn2

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingwild-type C57BL/6NTacUSA, heterozygous C57BL/6N

Disease and phenotype information

IMPC phenotypes (allele matching)
  • enlarged heart / IMPC
  • tremors / IMPC
  • hyperactivity / IMPC
  • decreased locomotor activity / IMPC
  • abnormal gait / IMPC
  • trunk curl / IMPC
  • increased circulating triglyceride level / IMPC
  • increased lean body mass / IMPC
  • increased circulating cholesterol level / IMPC
  • increased blood urea nitrogen level / IMPC
  • increased circulating total protein level / IMPC
IMPC phenotypes (gene matching)
  • decreased locomotor activity / IMPC
  • increased lean body mass / IMPC
  • increased blood urea nitrogen level / IMPC
  • abnormal gait / IMPC
  • enlarged heart / IMPC
  • increased circulating total protein level / IMPC
  • increased circulating triglyceride level / IMPC
  • hyperactivity / IMPC
  • increased circulating cholesterol level / IMPC
  • tremors / IMPC
  • trunk curl / IMPC
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • abnormal social investigation / MGI
  • increased anxiety-related response / MGI
  • postnatal lethality / MGI
  • no abnormal phenotype detected / MGI
  • increased vertical activity / MGI
  • abnormal inhibitory postsynaptic currents / MGI
  • abnormal response to novel object / MGI
  • nervous system phenotype / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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