IMPC phenotypes (gene matching)
- decreased prepulse inhibition / IMPC
C57BL/6NTac-Plaurem2(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:11642 |
| International strain name | C57BL/6NTac-Plaurem2(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Plaurem2(IMPC)H |
| Gene/Transgene symbol | Plaur |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTacUSA, heterozygous C57BL/6N |
Disease and phenotype information
MGI phenotypes (gene matching)
- myoclonus / MGI
- abnormal cerebral cortex morphology / MGI
- increased anxiety-related response / MGI
- decreased exploration in new environment / MGI
- increased inflammatory response / MGI
- liver inflammation / MGI
- increased susceptibility to bacterial infection / MGI
- abnormal macrophage physiology / MGI
- abnormal neutrophil physiology / MGI
- impaired neutrophil phagocytosis / MGI
- chronic inflammation / MGI
- increased susceptibility to pharmacologically induced seizures / MGI
- loss of cortex neurons / MGI
- loss of GABAergic neurons / MGI
- liver fibrosis / MGI
- abnormal brain interneuron morphology / MGI
- renal/urinary system phenotype / MGI
- homeostasis/metabolism phenotype / MGI
- growth/size/body region phenotype / MGI
- cardiovascular system phenotype / MGI
- behavior/neurological phenotype / MGI
- hematopoietic system phenotype / MGI
- decreased angiogenesis / MGI
- abnormal neuronal migration / MGI
- abnormal cytokine level / MGI
- trachea inflammation / MGI