IMPC phenotypes (allele matching)
C57BL/6NCrl-Mex3btm1b(KOMP)Wtsi/Ph
| Status | Available to order |
| EMMA ID | EM:11612 |
| International strain name | C57BL/6NCrl-Mex3btm1b(KOMP)Wtsi/Ph |
| Alternative name | EPD0729_5_A05 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Mex3btm1b(KOMP)Wtsi |
| Gene/Transgene symbol | Mex3b |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Institute of Molecular Genetics |
| Provider affiliation | Department of Transgenic Models of Diseases, Institute of Molecular Genetics |
| Genetic information | This mouse line originates from KOMP ES clone EPD0729_5_A05. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele (Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics (MGI:5285392)). Click here for more information on KOMP final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6NCrl |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- decreased body weight / MGI
- decreased body size / MGI
- impaired macrophage phagocytosis / MGI
- reduced fertility / MGI
- abnormal seminiferous tubule morphology / MGI
- oligozoospermia / MGI
- Sertoli cell hyperplasia / MGI
- no phenotypic analysis / MGI
- abnormal granulosa cell morphology / MGI
- decreased Sertoli cell phagocytosis / MGI
- neonatal lethality, incomplete penetrance / MGI
- abnormal seminiferous tubule epithelium morphology / MGI
- abnormal Sertoli cell barrier morphology / MGI
- abnormal Sertoli cell barrier function / MGI