- abnormal tibia morphology / IMPC
- abnormal femur morphology / IMPC
- abnormal autopod morphology / IMPC
- abnormal nail morphology / IMPC
- abnormal cornea morphology / IMPC
- abnormal digit morphology / IMPC
- abnormal joint morphology / IMPC
- vertebral transformation / IMPC
- polysyndactyly / IMPC
- fused phalanges / IMPC
- preweaning lethality, complete penetrance / IMPC
C57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg
Status | Available to order |
EMMA ID | EM:11574 |
Citation information | RRID:IMSR_EM:11574 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg |
Alternative name | |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Pitx1em1(IMPC)Wtsi |
Gene/Transgene symbol | Pitx1 |
Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Familial clubfoot due to PITX1 point mutation / Orphanet_293150
- Brachydactyly-elbow wrist dysplasia syndrome / Orphanet_1275
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- abnormal tibia morphology / IMPC
- abnormal cornea morphology / IMPC
- polysyndactyly / IMPC
- abnormal digit morphology / IMPC
- abnormal joint morphology / IMPC
- fused phalanges / IMPC
- abnormal nail morphology / IMPC
- abnormal autopod morphology / IMPC
- abnormal femur morphology / IMPC
- vertebral transformation / IMPC
- preweaning lethality, complete penetrance / IMPC
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