C57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg

Status

Available to order

EMMA IDEM:11574
International strain nameC57BL/6N-Pitx1em1(IMPC)Wtsi/WtsiIeg
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolPitx1em1(IMPC)Wtsi
Gene/Transgene symbolPitx1

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (allele matching)
  • abnormal tibia morphology / IMPC
  • abnormal femur morphology / IMPC
  • abnormal autopod morphology / IMPC
  • abnormal nail morphology / IMPC
  • abnormal cornea morphology / IMPC
  • abnormal digit morphology / IMPC
  • abnormal joint morphology / IMPC
  • vertebral transformation / IMPC
  • polysyndactyly / IMPC
  • fused phalanges / IMPC
  • preweaning lethality, complete penetrance / IMPC
IMPC phenotypes (gene matching)
  • abnormal tibia morphology / IMPC
  • abnormal cornea morphology / IMPC
  • polysyndactyly / IMPC
  • abnormal digit morphology / IMPC
  • abnormal joint morphology / IMPC
  • fused phalanges / IMPC
  • abnormal nail morphology / IMPC
  • abnormal autopod morphology / IMPC
  • abnormal femur morphology / IMPC
  • vertebral transformation / IMPC
  • preweaning lethality, complete penetrance / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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