C57BL/6N-Mkrn2em1(IMPC)Wtsi/WtsiOulu

Status

Available to order

EMMA IDEM:11573
International strain nameC57BL/6N-Mkrn2em1(IMPC)Wtsi/WtsiOulu
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolMkrn2em1(IMPC)Wtsi
Gene/Transgene symbolMkrn2

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreUniversity of Oulu, Oulu, Finland

Disease and phenotype information

IMPC phenotypes (allele matching)
  • male infertility / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
IMPC phenotypes (gene matching)
  • male infertility / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • decreased mean corpuscular hemoglobin concentration / IMPC
  • decreased dendritic epidermal T cell number / IMPC
  • abnormal auditory brainstem response / IMPC
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • male infertility / MGI
  • asthenozoospermia / MGI
  • oligozoospermia / MGI
  • abnormal Sertoli cell morphology / MGI
  • abnormal spermiation / MGI
  • decreased testis weight / MGI
  • abnormal spermatid morphology / MGI
  • abnormal sperm flagellum morphology / MGI
  • abnormal acrosome morphology / MGI
  • abnormal sperm head morphology / MGI
  • abnormal sperm axoneme morphology / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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