IMPC phenotypes (allele matching)
C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg
| Status | Available to order |
| EMMA ID | EM:11572 |
| International strain name | C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Brd2em1(IMPC)Wtsi |
| Gene/Transgene symbol | Brd2 |
Information from provider
| Provider | Wellcome Trust Sanger Institute |
| Provider affiliation | Wellcome Trust Sanger Institute |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal adipose tissue morphology / MGI
- abnormal vertebral body morphology / MGI
- rib bifurcation / MGI
- rib fusion / MGI
- scoliosis / MGI
- enlarged heart / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- abnormal cell death / MGI
- decreased cell proliferation / MGI
- abnormal craniofacial morphology / MGI
- increased rib number / MGI
- enlarged liver sinusoidal spaces / MGI
- abnormal pineal gland morphology / MGI
- small thymus / MGI
- abnormal forebrain morphology / MGI
- abnormal embryonic neuroepithelial layer differentiation / MGI
- abnormal choroid plexus morphology / MGI
- exencephaly / MGI
- absent superior cervical ganglion / MGI
- abnormal vagus ganglion morphology / MGI
- obese / MGI
- abnormal eating behavior / MGI
- increased circulating triglyceride level / MGI
- abnormal embryo size / MGI
- decreased embryo size / MGI
- hemorrhage / MGI
- increased circulating insulin level / MGI
- abnormal neural tube morphology / MGI
- abnormal nasal septum morphology / MGI
- hepatic steatosis / MGI
- persistent truncus arteriosis / MGI
- increased circulating glucagon level / MGI
- abnormal semilunar valve morphology / MGI
- abnormal aortic valve morphology / MGI
- abnormal pulmonary valve morphology / MGI
- small thyroid gland / MGI
- small kidney / MGI
- abnormal cell cycle / MGI
- aphakia / MGI
- decreased rib number / MGI
- aorta coarctation / MGI
- increased pancreatic beta cell number / MGI
- abnormal neural tube closure / MGI
- abnormal circulating lipid level / MGI
- embryonic growth retardation / MGI
- thin myocardium compact layer / MGI
- transposition of great arteries / MGI
- abnormal respiratory quotient / MGI
- retroesophageal right subclavian artery / MGI
- abnormal adenohypophysis morphology / MGI
- fetal growth retardation / MGI
- abnormal embryonic neuroepithelium morphology / MGI
- abnormal optic stalk morphology / MGI
- abnormal optic cup morphology / MGI
- basisphenoid bone foramen / MGI
- absent vagus nerve / MGI
- abnormal vertebral arch morphology / MGI
- absent vertebral arch / MGI
- fusion of vertebral arches / MGI
- increased adiponectin level / MGI
- abnormal gallbladder morphology / MGI
- abnormal middle ear ossicle morphology / MGI
- increased circulating cholesterol level / MGI
- abnormal pancreatic islet morphology / MGI
- abnormal olfactory nerve morphology / MGI
- improved glucose tolerance / MGI
- pancreatic islet hyperplasia / MGI
- decreased circulating glucose level / MGI
- increased circulating leptin level / MGI
- increased fat cell size / MGI
- artery stenosis / MGI
- increased circulating tumor necrosis factor level / MGI
- increased circulating interleukin-1 beta level / MGI
- thoracoschisis / MGI
- increased basal metabolism / MGI
- increased pancreatic islet number / MGI
- increased epididymal fat pad weight / MGI
- increased interscapular fat pad weight / MGI
- abnormal blood homeostasis / MGI
- abnormal optic chiasm morphology / MGI
- increased total body fat amount / MGI
- atrioventricular septal defect / MGI
- perimembraneous ventricular septal defect / MGI
- muscular ventricular septal defect / MGI
- abnormal pectinate muscle morphology / MGI
- persistent right dorsal aorta / MGI
- common truncal valve / MGI
- abnormal lung position or orientation / MGI
- postnatal lethality, incomplete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- enlarged brain ventricles / MGI
- interrupted aortic arch, type b / MGI
- dual inferior vena cava / MGI
- myelocele / MGI
- increased embryonic neuroepithelium apoptosis / MGI
- increased embryonic neuroepithelium thickness / MGI
- abnormal common carotid artery morphology / MGI
- increased embryonic tissue cell apoptosis / MGI
- absent pectinate muscle / MGI
- abnormal hepatic portal vein connection / MGI
- abnormal hypoglossal nerve topology / MGI
- retropleural edema / MGI
- subcutaneous edema / MGI
- abnormal Mullerian duct topology / MGI
- abnormal ductus venosus morphology / MGI
- abnormal ductus venosus topology / MGI
- duplication of ductus venosus / MGI
- absent costovertebral joint / MGI
- absent eye muscles / MGI
- abnormal thymus topology / MGI
- reduced sympathetic cervical ganglion size / MGI
- absent connection between subcutaneous lymph vessels and lymph sac / MGI
- blood in lymph vessels / MGI
- abnormal umbilical vein topology / MGI
- abnormal external carotid artery origin / MGI
- abnormal vertebral artery topology / MGI
- heterochrony / MGI
- abnormal brain artery topology / MGI
- persistent trigeminal artery / MGI
- abnormal physiological umbilical hernia morphology / MGI