B6.C(129)-Tg(CMV-cre)1Cgn/CgnCnrm
| Status | Available to order |
| EMMA ID | EM:01149 |
| International strain name | B6.C(129)-Tg(CMV-cre)1Cgn/CgnCnrm |
| Alternative name | B6.129-Cre-Deleter |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CMV-cre)1Cgn |
| Gene/Transgene symbol | Tg(CMV-cre)1Cgn |
Information from provider
| Provider | Klaus Rajewsky |
| Provider affiliation | CBR Institute for Biomedical Research, Immune Disease Institute |
| Genetic information | Original transgene construct for the expression of cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most mouse cells and tissues. |
| Phenotypic information | Original cre recombinase-expressing transgenic mouse strain for the ubiquitous deletion in vivo ("deleter strain") of loxP-flanked gene segments. |
| Breeding history | Backcrossed to 129 (more than 5 generations) then backcrossed to C57BL/6 (7-8 generations) |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | heterozygous C57BL/6, wild-type C57BL/6 |
| Stage of embryos | 8-cell |
Literature references
- A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells.;Schwenk F, Baron U, Rajewsky K, ;1995;Nucleic acids research;23;5080-1; 8559668
- Liver-derived ketone bodies are necessary for food anticipation.;Chavan Rohit, Feillet Céline, Costa Sara S Fonseca, Delorme James E, Okabe Takashi, Ripperger Jürgen A, Albrecht Urs, ;2016;Nature communications;7;10580; 26838474
- PER2 mediates CREB-dependent light induction of the clock gene Per1.;Brenna Andrea, Ripperger Jürgen A, Saro Gabriella, Glauser Dominique A, Yang Zhihong, Albrecht Urs, ;2021;Scientific reports;11;21766; 34741086