IMPC phenotypes (gene matching)
- increased exploration in new environment / IMPC
C57BL/6NTac-Cntnap2em2(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:11402 |
| International strain name | C57BL/6NTac-Cntnap2em2(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Cntnap2em2(IMPC)H |
| Gene/Transgene symbol | Cntnap2 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | wild-type C57BL/6NTacUSA, heterozygous C57BL/6NTacUSA |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Pitt-Hopkins-like syndrome / Orphanet_221150
- Cortical dysplasia-focal epilepsy syndrome / Orphanet_163681
MGI phenotypes (gene matching)
- abnormal corpus callosum morphology / MGI
- decreased body size / MGI
- social withdrawal / MGI
- hyperactivity / MGI
- increased stereotypic behavior / MGI
- increased grooming behavior / MGI
- abnormal nest building behavior / MGI
- abnormal motor coordination/balance / MGI
- abnormal olfaction / MGI
- seizures / MGI
- astrocytosis / MGI
- abnormal response to novel odor / MGI
- nervous system phenotype / MGI
- decreased thermal nociceptive threshold / MGI
- abnormal brain interneuron morphology / MGI
- abnormal neuron physiology / MGI
- abnormal brain wave pattern / MGI
- behavior/neurological phenotype / MGI
- abnormal neuronal migration / MGI
- environmentally induced seizures / MGI
- cognitive inflexibility / MGI
- abnormal inhibitory learning / MGI
- decreased vocalization / MGI