B6.Cg-Tg(Camk2a-cre)93Kln/KlnCnrm
| Status | Available to order |
| EMMA ID | EM:01137 |
| Citation information | RRID:IMSR_EM:01137 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Camk2a-cre)93Kln/KlnCnrm |
| Alternative name | AlphaCaMKII-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Camk2a-cre)93Kln |
| Gene/Transgene symbol | Tg(Camk2a-cre)93Kln |
Information from provider
| Provider | Klaus Rajewsky |
| Provider affiliation | CBR Institute for Biomedical Research, Immune Disease Institute |
| Genetic information | The CamK-cre93 transgene directs the expression of cre recombinase under the control of the calcium/calmodulin-dependent protein kinase II promoter. The promoter is active starting at P21 in the cortex, hippocampus, hypothalamus and brainstem, but not in glia. |
| Phenotypic information | The strain is used for in vivo cre-mediated recombination, under the control of the calcium/calmodulin-dependent protein kinase II promoter. The promoter is active starting at P21 in the cortex, hippocampus, hypothalamus and brainstem, but not in glia. |
| Breeding history | Mixed 129 x CBA background, backcrossed to C57BL/6 (5-6 generations). |
| References |
|
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Essential role for TrkB receptors in hippocampus-mediated learning.;Minichiello L, Korte M, Wolfer D, Kühn R, Unsicker K, Cestari V, Rossi-Arnaud C, Lipp H P, Bonhoeffer T, Klein R, ;1999;Neuron;24;401-14; 10571233