B6.C-Tg(CMV-cre)1Cgn/CgnCnrm
| Status | Available to order |
| EMMA ID | EM:01135 |
| International strain name | B6.C-Tg(CMV-cre)1Cgn/CgnCnrm |
| Alternative name | B6-Cre-Deleter |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CMV-cre)1Cgn |
| Gene/Transgene symbol | Tg(CMV-cre)1Cgn |
Information from provider
| Provider | Klaus Rajewsky |
| Provider affiliation | CBR Institute for Biomedical Research, Immune Disease Institute |
| Genetic information | Original transgene construct for the expression of cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most mouse cells and tissues. |
| Phenotypic information | Original cre recombinase-expressing transgenic mouse strain for the ubiquitous deletion in vivo ("deleter strain") of loxP-flanked gene segments. Homozygous breeding. |
| Breeding history | Backcrossed to C57BL/6 (more than 10 generations) |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells.;Schwenk F, Baron U, Rajewsky K, ;1995;Nucleic acids research;23;5080-1; 8559668
- Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling.;Donati Viola, Peres Chiara, Nardin Chiara, Scavizzi Ferdinando, Raspa Marcello, Ciubotaru Catalin D, Bortolozzi Mario, Pedersen Morten Gram, Mammano Fabio, ;2022;Function (Oxford, England);3;zqab064; 35330924