IMPC phenotypes (allele matching)
C57BL/6NTac-Grm7em1(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:11317 |
| International strain name | C57BL/6NTac-Grm7em1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Grm7em1(IMPC)H |
| Gene/Transgene symbol | Grm7 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTac |
| Breeding at archiving centre | Maintained on a C57BL/6NTac background |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive non-syndromic intellectual disability / Orphanet_88616
- Early infantile epileptic encephalopathy / Orphanet_1934
MGI phenotypes (gene matching)
- convulsive seizures / MGI
- impaired coordination / MGI
- abnormal contextual conditioning behavior / MGI
- seizures / MGI
- hyperresponsive to tactile stimuli / MGI
- abnormal conditioned taste aversion behavior / MGI
- increased susceptibility to pharmacologically induced seizures / MGI
- abnormal excitatory postsynaptic currents / MGI
- nervous system phenotype / MGI
- abnormal spatial working memory / MGI
- increased sensitivity to xenobiotic induced morbidity/mortality / MGI