C57BL/6N-Crlf3em1(IMPC)Wtsi/WtsiH

Status

Available to order

EMMA IDEM:11159
International strain nameC57BL/6N-Crlf3em1(IMPC)Wtsi/WtsiH
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolCrlf3em1(IMPC)Wtsi
Gene/Transgene symbolCrlf3

Information from provider

Provider Wellcome Trust Sanger Institute
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingheterozygous C57BL/6NTacUSA
Breeding at archiving centreC57BL/6NTac background

Disease and phenotype information

IMPC phenotypes (allele matching)
  • thrombocytopenia / IMPC
  • increased red blood cell distribution width / IMPC
IMPC phenotypes (gene matching)
  • increased circulating iron level / IMPC
  • decreased body weight / IMPC
  • thrombocytopenia / IMPC
  • increased red blood cell distribution width / IMPC
  • abnormal behavior / IMPC
  • decreased mean corpuscular volume / IMPC
  • tremors / IMPC
MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • decreased lean body mass / MGI
  • increased hemoglobin content / MGI
  • increased mean corpuscular hemoglobin concentration / MGI
  • decreased mean corpuscular hemoglobin concentration / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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