IMPC phenotypes (gene matching)
Otp-CreER
| Status | Available to order |
| EMMA ID | EM:11121 |
| International strain name | Otp-CreER |
| Alternative name | Otp-CreER |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Otp-creER |
| Gene/Transgene symbol | Otp |
Information from provider
| Provider | Antonio Simeone |
| Provider affiliation | IGB-CNR |
| Genetic information | Tamoxifen-inducible Cre recombinase under transcriptional control of orthopedia gene, by gene replacement. |
| Phenotypic information | Homozygous:Mice die at birth.Heterozygous:Mice are viable and fertile. |
| References | None available |
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased brain size / MGI
- abnormal third ventricle morphology / MGI
- abnormal diencephalon morphology / MGI
- abnormal hypothalamus morphology / MGI
- decreased body weight / MGI
- decreased body size / MGI
- abnormal dopaminergic neuron morphology / MGI
- abnormal neurohypophysis morphology / MGI
- abnormal hypothalamus physiology / MGI
- abnormal paraventricular hypothalamic nucleus morphology / MGI
- abnormal supraoptic nucleus morphology / MGI
- abnormal neurohypophysis median eminence morphology / MGI
- postnatal lethality, complete penetrance / MGI