IMPC phenotypes (gene matching)
C57BL/6N-Rasgrf1tm1aNarl/H
| Status | Available to order |
| EMMA ID | EM:11111 |
| Citation information | RRID:IMSR_EM:11111 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Rasgrf1tm1aNarl/H |
| Alternative name | WCW_1413_003 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Rasgrf1tm1aNarl |
| Gene/Transgene symbol | Rasgrf1 |
Information from provider
| Provider | NLAC, National Laboratory Animal Center |
| Provider affiliation | NLAC, National Laboratory Animal Center |
| Genetic information | The targeting cassette was designed based on the EUCOMM strategy. Briefly a lacZ/Pgk-Neo cassette flanked by two Frt sites, was inserted 5' to the critical exon(s). LoxP sites are found either side of the Pgk-Neo element and a further LoxP site is found 3' of the critical exon(s). |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTac (USA) males |
| Breeding at archiving centre | C57BL/6NTac background |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased body weight / MGI
- abnormal spatial learning / MGI
- reduced long term potentiation / MGI
- postnatal growth retardation / MGI
- abnormal pituitary secretion / MGI
- impaired synaptic plasticity / MGI
- no abnormal phenotype detected / MGI
- decreased circulating insulin level / MGI
- abnormal active avoidance behavior / MGI
- abnormal discrimination learning / MGI
- abnormal excitatory postsynaptic potential / MGI
- impaired social transmission of food preference / MGI
- no phenotypic analysis / MGI
- maternal imprinting / MGI
- paternal imprinting / MGI
- decreased pancreatic beta cell number / MGI
- nervous system phenotype / MGI
- abnormal imprinting / MGI
- decreased circulating insulin-like growth factor I level / MGI
- decreased growth hormone level / MGI
- impaired glucose tolerance / MGI
- behavior/neurological phenotype / MGI
- enhanced lipolysis / MGI
- abnormal long term spatial reference memory / MGI
- abnormal DNA methylation / MGI
- small pancreatic islets / MGI
- impaired contextual conditioning behavior / MGI
- decreased total body fat amount / MGI