IMPC phenotypes (gene matching)
C57BL/6N-Rasgrf1tm1aNarl/H
| Status | Available to order |
| EMMA ID | EM:11111 |
| International strain name | C57BL/6N-Rasgrf1tm1aNarl/H |
| Alternative name | WCW_1413_003 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Rasgrf1tm1aNarl |
| Gene/Transgene symbol | Rasgrf1 |
Information from provider
| Provider | NLAC, National Laboratory Animal Center |
| Provider affiliation | NLAC, National Laboratory Animal Center |
| Genetic information | The targeting cassette was designed based on the EUCOMM strategy. Briefly a lacZ/Pgk-Neo cassette flanked by two Frt sites, was inserted 5' to the critical exon(s). LoxP sites are found either side of the Pgk-Neo element and a further LoxP site is found 3' of the critical exon(s). |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6NTacUSA |
| Breeding at archiving centre | C57BL/6NTac background |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased body weight / MGI
- abnormal spatial learning / MGI
- reduced long term potentiation / MGI
- postnatal growth retardation / MGI
- abnormal pituitary secretion / MGI
- impaired synaptic plasticity / MGI
- no abnormal phenotype detected / MGI
- decreased circulating insulin level / MGI
- abnormal active avoidance behavior / MGI
- abnormal discrimination learning / MGI
- abnormal excitatory postsynaptic potential / MGI
- impaired social transmission of food preference / MGI
- no phenotypic analysis / MGI
- maternal imprinting / MGI
- paternal imprinting / MGI
- decreased pancreatic beta cell number / MGI
- nervous system phenotype / MGI
- abnormal imprinting / MGI
- decreased circulating insulin-like growth factor I level / MGI
- decreased growth hormone level / MGI
- impaired glucose tolerance / MGI
- behavior/neurological phenotype / MGI
- enhanced lipolysis / MGI
- abnormal long term spatial reference memory / MGI
- abnormal DNA methylation / MGI
- small pancreatic islets / MGI
- impaired contextual conditioning behavior / MGI
- decreased total body fat amount / MGI