IMPC phenotypes (allele matching)
C57BL/6-Setdb2tm1a(KOMP)Wtsi/Biat
| Status | Available to order |
| EMMA ID | EM:11046 |
| Citation information | RRID:IMSR_EM:11046 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Setdb2tm1a(KOMP)Wtsi/Biat |
| Alternative name | Setdb2 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Setdb2tm1a(KOMP)Wtsi |
| Gene/Transgene symbol | Setdb2 |
Information from provider
| Provider | David Symer |
| Provider affiliation | Dept. of Lymphoma & Myeloma, Univ. Texas MD Anderson Cancer Center |
| Genetic information | A gene-trap construct together with loxP sites were introduced up- and downstream of exon 6 of Setdb2. The knockout first allele is initially a non-expressive form, but can be converted to a conditional allele via flp recombinase-mediated recombination. |
| Phenotypic information | Homozygous:altered immune responseHeterozygous:not performed |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | yes |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | homozygous C57BL/6 males |