B6;C3-Tg(GFAP-SRC)2Aag/Cnrm
| Status | Available to order |
| EMMA ID | EM:00109 |
| Citation information | RRID:IMSR_EM:00109 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;C3-Tg(GFAP-SRC)2Aag/Cnrm |
| Alternative name | GFAPv-src-Tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(GFAP-SRC)2Aag |
| Gene/Transgene symbol | Tg(GFAP-SRC)2Aag |
Information from provider
| Provider | Adriano Aguzzi |
| Provider affiliation | Univ.Hosp.Zurich/Inst.Neuropathology |
| Genetic information | Astrocyte-specific expression of v-SRC kinase. Insertion of v-SRC into exon 1 of a 17kb expression construct, consisting of the entire exon/intron structure of the mouse GFAP gene plus SV40 late gene splicing and polyadenylation signal in exon 1 (copy number 32). |
| Breeding history | Crossed to C57BL/6 then intercrossed |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
MGI allele-associated human disease models
Literature references
- Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice.;Weissenberger J, Steinbach J P, Malin G, Spada S, Rülicke T, Aguzzi A, ;1997;Oncogene;14;2005-13; 9160879